The Science

WHAT IS SPERMIDINE?

YOU HAVE A DIRTY MIND, YOU WENT THERE AND GUESS WHAT, YOU'RE RIGHT, SPERMIDINE WAS ORIGINALLY DISCOVERED IN SEMEN AND WAS LATER FOUND TO EXIST IN ALL LIVING CELLS

  • First discovered in 1678 by Antonie van Leeuwenhoek
  • Spermidine is a natural polyamine that exists in our cells. With increasing age, the level of spermidine in the cells decreases.
  • Research shows spermidine inhibits five of the nine hallmarks of aging and has almost no known side effects.
  • As well as stabilising mitochondrial DNA, spermidine is a regulator of autophagy, the body’s cellular renewal and recycling process that slows as we age.
  • In addition to being a neuroprotector, spermidine was found to trigger some of the same responses as caloric restriction or fasting, which is also associated with increased lifespan.
  • Spermidine enhances brain health, improves physical signs of youth, such as thicker hair growth and much more....

 

Clinical trials, research & studies

Dig into the research by reading some of the best clinical trials and studies on spermidine

Research

Glossary of definitions

  • Autophagy

    It allows for the orderly degradation and recycling of cellular components, effectively helping one's body renew its cells. Insufficient autophagy is thought to be one of the main reasons for the accumulation of damaged cells and aging.

  • Mitochondria

    Commonly known as the powerhouse of the cell, Mitochondria play a critical role in the generation of metabolic energy in human cells. They are responsible for most of the useful energy derived from the breakdown of carbohydrates and fatty acids, which is converted to ATP by the process of oxidative phosphorylation.

  • Polyamines

    Polyamines are essential for cell proliferation. Polyamine content is higher in rapidly growing tissues, and regenerative and growth-promoting hormonal stimuli enhance polyamine synthesis and content.

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